Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Atropine
Drug ID BADD_D00189
Description An alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
Indications and Usage For the treatment of poisoning by susceptible organophosphorous nerve agents having anti-cholinesterase activity (cholinesterase inhibitors) as well as organophosphorous or carbamate insecticides.
Marketing Status approved; vet_approved
ATC Code A03BA01; S01FA01
DrugBank ID DB00572
KEGG ID D00113
MeSH ID D001285
PubChem ID 174174
TTD Drug ID D0RG3O
NDC Product Code 69205-034; 11704-101; 13371-488; 11704-104; 11704-107; 11704-105; 12714-034; 11704-106; 60592-049; 63827-1015; 64181-0048
UNII 7C0697DR9I
Synonyms Atropine | Atropinol | Atropine Sulfate | Sulfate, Atropine | Atropine Sulfate Anhydrous | Anhydrous, Atropine Sulfate | Sulfate Anhydrous, Atropine | AtroPen | Atropin Augenöl | Augenöl, Atropin
Chemical Information
Molecular Formula C17H23NO3
CAS Registry Number 51-55-8
SMILES CN1C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypohidrosis23.02.03.005; 08.01.03.029--
Hypokalaemia14.05.03.002--
Hyponatraemia14.05.04.002--
Hypotension24.06.03.0020.000372%
Hypotonia17.05.02.002; 15.05.04.0080.000138%Not Available
Ileus paralytic07.02.05.001--Not Available
Impaired gastric emptying07.02.02.004--
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Intraocular pressure increased13.07.04.002--Not Available
Irritability08.01.03.011; 19.04.02.013--
Keratitis06.04.02.002--
Labile blood pressure24.06.01.001--Not Available
Lacrimation decreased06.08.02.007--Not Available
Laryngitis22.07.03.001; 11.01.13.001--
Laryngospasm22.04.02.002--
Left ventricular failure02.05.02.001--Not Available
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Leukocytosis01.02.01.002--
Loss of consciousness17.02.04.004--Not Available
Loss of libido19.08.03.003--Not Available
Mania19.16.02.002--
Miosis17.02.11.002; 06.05.03.0030.000138%Not Available
Mucosal dryness08.01.06.0010.000138%Not Available
Muscle twitching15.05.03.005--Not Available
Mydriasis17.02.11.003; 06.05.03.0040.001033%Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Myopia06.02.04.002--Not Available
Nasal congestion22.04.04.001--
Nasal dryness22.04.03.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene