| Pharmaceutical Information |
| Drug Name |
Azathioprine sodium |
| Drug ID |
BADD_D00196 |
| Description |
Azathioprine is a prodrug of 6-mercaptopurine, first synthesized in 1956 by Gertrude Elion, William Lange, and George Hitchings in an attempt to produce a derivative of 6-mercaptopurine with a better therapeutic index.[A189678,A189687,A189690] Azathioprine is used to treat inflammatory conditions like rheumatoid arthritis and as an immunosuppressant in the prevention of renal transplant rejection.[L11214]
Azathiprine was granted FDA approval on 20 March 1968.[L11214] |
| Indications and Usage |
Azathioprine is indicated to treat rheumatoid arthritis and prevent renal transplant rejection.[L11214] |
| Marketing Status |
approved |
| ATC Code |
L04AX01 |
| DrugBank ID |
DB00993
|
| KEGG ID |
D03033
|
| MeSH ID |
D001379
|
| PubChem ID |
11529527
|
| TTD Drug ID |
D07QCE
|
| NDC Product Code |
0143-9566 |
| UNII |
AM94R510MS
|
| Synonyms |
Azathioprine | Azothioprine | Imurel | Imuran | Immuran | Azathioprine Sodium | Sodium, Azathioprine | Azathioprine Sodium Salt | Azathioprine Sulfate |
|
| Chemical Information |
| Molecular Formula |
C9H6N7NaO2S |
| CAS Registry Number |
55774-33-9 |
| SMILES |
CN1C=NC(=C1SC2=NC=NC3=C2N=C[N-]3)[N+](=O)[O-].[Na+] |
| Chemical Structure |
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| ADRs Induced by Drug |
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