| Pharmaceutical Information |
| Drug Name |
Azelaic acid |
| Drug ID |
BADD_D00197 |
| Description |
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by _Malassezia furfur_, also known as _Pityrosporum ovale_, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such as mild to moderate acne, when applied topically in a cream formulation of 20%. It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear. Azelaic acid's antimicrobial action may be attributable to inhibition of microbial cellular protein synthesis. |
| Indications and Usage |
For the topical treatment of mild-to-moderate inflammatory acne vulgaris. |
| Marketing Status |
approved |
| ATC Code |
D10AX03 |
| DrugBank ID |
DB00548
|
| KEGG ID |
D03034
|
| MeSH ID |
C010038
|
| PubChem ID |
2266
|
| TTD Drug ID |
D0E4WR
|
| NDC Product Code |
0781-7172; 60862-007; 51552-0112; 76003-0026; 50222-303; 71052-638; 50090-4473; 16110-869; 68462-626; 48041-4700; 48041-4701; 51927-5188; 54236-050; 66039-911; 0591-2131; 51672-1389; 0115-1624; 50222-505 |
| UNII |
F2VW3D43YT
|
| Synonyms |
azelaic acid | nonanedioic acid | azelaic acid, dilithium salt | azelaic acid, dipotassium salt | monosodium azelate | azelaic acid, monosodium salt | azelaic acid, potassium salt | azelaic acid, sodium salt | Azelex | Finacea | skinoren | azelaic acid, disodium salt |
|
| Chemical Information |
| Molecular Formula |
C9H16O4 |
| CAS Registry Number |
123-99-9 |
| SMILES |
C(CCCC(=O)O)CCCC(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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