| Pharmaceutical Information |
| Drug Name |
Benazepril |
| Drug ID |
BADD_D00227 |
| Description |
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836]. |
| Indications and Usage |
Benazepril is indicated for the treatment of hypertension[A840]. It may be used alone or in combination with thiazide diuretics[FDA Label]. |
| Marketing Status |
approved; investigational |
| ATC Code |
C09AA07 |
| DrugBank ID |
DB00542
|
| KEGG ID |
D07499
|
| MeSH ID |
C044946
|
| PubChem ID |
5362124
|
| TTD Drug ID |
D0U3EC
|
| NDC Product Code |
61919-739 |
| UNII |
UDM7Q7QWP8
|
| Synonyms |
benazepril | benazapril | benzazepril | Labopal | Lotensin | Cibacène | Cibacen | Briem | benazepril hydrochloride | CGS-14824-A | CGS-14824A |
|
| Chemical Information |
| Molecular Formula |
C24H28N2O5 |
| CAS Registry Number |
86541-75-5 |
| SMILES |
CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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