Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Betaxolol hydrochloride
Drug ID BADD_D00264
Description A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Indications and Usage For the management of hypertension.
Marketing Status approved; investigational
ATC Code S01ED02; C07AB05
DrugBank ID DB00195
KEGG ID D00598
MeSH ID D015784
PubChem ID 107952
TTD Drug ID D03ROX
NDC Product Code 14445-002; 17337-0503; 10702-014; 0078-0729; 59349-0005; 0065-0246; 61314-245; 17478-705; 10702-013
UNII 6X97D2XT0O
Synonyms Betaxolol | Betaxolol Hydrochloride | Hydrochloride, Betaxolol | Kerlone | Oxodal | Kerlon | SL-75212 | SL 75212 | SL75212 | ALO-1401-02 | ALO 1401 02 | ALO140102 | Betoptic | Betoptima | Betaxolol Alcon | Alcon, Betaxolol
Chemical Information
Molecular Formula C18H30ClNO3
CAS Registry Number 63659-19-8
SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Alopecia23.02.02.001--
Asthma22.03.01.002; 10.01.03.010--Not Available
Atrioventricular block02.03.01.002--Not Available
Bradycardia02.03.02.002--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac failure congestive02.05.01.002--Not Available
Depression19.15.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Erythema23.03.06.001--Not Available
Glossitis07.14.01.001--Not Available
Headache17.14.01.001--
Hypoaesthesia eye17.02.06.019; 06.01.01.007--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Myasthenia gravis17.05.04.001; 15.05.08.001; 10.04.05.001--
Oedema14.05.06.010; 08.01.07.006--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Respiratory failure22.02.06.002; 14.01.04.003--
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Urticaria10.01.06.001; 23.04.02.001--
Vertigo17.02.12.002; 04.04.01.003--
Vital dye staining cornea present13.07.04.010--Not Available
Increased bronchial secretion22.12.01.002--Not Available
Anisocoria17.02.11.009; 06.05.03.013--Not Available
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