Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bezafibrate
Drug ID BADD_D00270
Description Antilipemic agent that lowers cholesterol and triglycerides. It decreases low density lipoproteins and increases high density lipoproteins.
Indications and Usage For the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus).
Marketing Status approved; investigational
ATC Code C10AB02
DrugBank ID DB01393
KEGG ID D01366
MeSH ID D001629
PubChem ID 39042
TTD Drug ID D00WCX
NDC Product Code 17337-0094
UNII Y9449Q51XH
Synonyms Bezafibrate | Solibay | Eulitop | durabezur | Azufibrat | Befibrat | Beza-Lande | Beza Lande | Beza-Puren | Beza Puren | Bezabeta | Bezacur | Bezafibrat PB | Bezafisal | Bezalip | Bezamerck | BM-15.075 | BM 15.075 | BM15.075 | Cedur | Lipox | Reducterol | Regadrin B | Sklerofibrat | Béfizal | Difaterol
Chemical Information
Molecular Formula C19H20ClNO4
CAS Registry Number 41859-67-0
SMILES CC(C)(C(=O)O)OC1=CC=C(C=C1)CCNC(=O)C2=CC=C(C=C2)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Myositis15.05.01.001--
Nausea07.01.07.001--
Pain08.01.08.004--
Pancytopenia01.03.03.003--Not Available
Pharyngitis07.05.07.004; 22.07.03.004; 11.01.13.003--
Photosensitivity reaction23.03.09.003--
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Rash23.03.13.001--Not Available
Rhabdomyolysis15.05.05.002--
Stevens-Johnson syndrome11.07.01.005; 10.01.01.045; 23.03.01.007; 12.03.01.014--
Tenosynovitis15.07.01.004--Not Available
Thrombocytopenia01.08.01.002--Not Available
Toxic epidermal necrolysis12.03.01.015; 11.07.01.006; 10.01.01.006; 23.03.01.008--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura23.06.01.008; 01.01.04.007; 24.07.06.011--Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Transaminases increased13.03.04.036--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Acute kidney injury20.01.03.016--
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