Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bisacodyl
Drug ID BADD_D00276
Description Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]
Indications and Usage Bisacodyl is indicated to relieve occasional constipation and irregularity.[L13362]
Marketing Status approved
ATC Code A06AB02; A06AG02
DrugBank ID DB09020
KEGG ID D00245
MeSH ID D001726
PubChem ID 2391
TTD Drug ID D07IEF
NDC Product Code 80136-871; 61876-0002; 30142-827; 41167-0290; 41415-121; 55315-190; 63941-120; 63941-190; 68016-688; 68210-3120; 68210-4106; 71335-2010; 12828-0015; 38779-3146; 51927-0115; 21130-676; 24689-129; 36800-190; 37808-676; 41163-195; 41167-0200; 41167-0400; 41250-191; 50804-327; 62011-0403; 67091-215; 68163-116; 58793-002; 10237-906; 11822-0327; 36800-676; 41520-019; 49035-327; 53943-805; 55319-327; 55910-120; 57896-443; 59779-706; 63940-327; 69846-140; 70795-1010; 72476-845; 72476-960; 55910-457; 56062-676; 57896-441; 67091-385; 70000-0538; 71610-453; 71890-330; 16990-010; 68210-1022; 21130-827; 36800-327; 41163-607; 50844-697; 59779-676; 0363-0327; 69842-816; 70000-0570; 70000-0573; 70518-2976; 0904-6748; 11822-0676; 11822-7850; 24385-903; 41167-0101; 41226-003; 41226-151; 41250-339; 41415-116; 49483-003; 55910-850; 57648-002; 70677-1091; 11673-151; 41250-676; 43749-460; 46122-529; 49348-032; 53943-676; 59726-190; 63868-573; 67091-286; 68016-197; 68784-102; 69618-058; 69842-089; 70518-1864; 0574-7050; 71335-1531; 71399-8460; 79903-178; 12579-228; 69617-008; 83221-001; 37808-327; 55301-676; 55910-327; 58980-415; 59779-327; 62011-0277; 0363-3011; 0363-6760; 63868-209; 68016-084; 68998-398; 70000-0221; 70000-0228; 70677-1086; 76457-003; 62485-036; 11673-116; 21130-410; 41167-0210; 41250-665; 49035-706; 50844-327; 55319-195; 56062-327; 63868-328; 63868-908; 71335-1750; 72476-654; 0904-6407; 49706-0650; 30142-191; 37808-877; 46122-429; 50804-190; 55319-607; 55910-168; 55910-190; 55910-253; 63868-572; 71335-1754; 71610-700; 72701-102; 81440-102; 12579-230; 0904-7142; 11822-0790; 33992-0327; 0132-0703; 46122-608; 50804-120; 55154-6897; 55910-954
UNII 10X0709Y6I
Synonyms Bisacodyl | Durolax | Apo-Bisacodyl | Apo Bisacodyl | Bekunis Bisacodyl | Bisacodyl, Bekunis | Bicol | Bisac-Evac | Bisac Evac | Bisacodyl Tannex | Tannex, Bisacodyl | Bisacodyl Uniserts | Uniserts, Bisacodyl | Ulcolax | Bisalax | Bisco-Lax | Bisco Lax | Lünolax | Bisco-Zitron | Bisco Zitron | Dulcolax | Dulco-Lax | Dulco Lax | Fleet Bisacodyl | Bisacodyl, Fleet | Laxagetten | Laxanin | Laxans-ratiopharm | Laxans ratiopharm | Laxbene | Laxysat Bürger | Florisan N | ratio-Bisacodyl | ratio Bisacodyl | Dulco-lax perles | Dulco lax perles | Dulcolax perles | Rytmil | Agaroletten
Chemical Information
Molecular Formula C22H19NO4
CAS Registry Number 603-50-9
SMILES CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.003--
Abdominal rigidity07.01.05.011--Not Available
Ageusia17.02.07.001; 07.14.03.003--Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Asthenia08.01.01.001--Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chills15.05.03.016; 08.01.09.001--
Cold sweat23.02.03.002; 08.01.03.024--Not Available
Colitis07.08.01.001--
Colitis ischaemic24.04.08.012; 07.08.01.004--Not Available
Constipation07.02.02.001--
Dehydration14.05.05.001--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Drug abuse19.07.06.010--Not Available
Drug dependence19.07.06.011--Not Available
Drug ineffective08.06.01.006--Not Available
Dry mouth07.06.01.002--
Feeling abnormal08.01.09.014--Not Available
Feeling hot08.01.09.009--Not Available
Flatulence07.01.04.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
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ADReCS-Target
Drug Name ADR Term Target
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