Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bromfenac
Drug ID BADD_D00300
Description Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool to optimize surgical outcomes.
Indications and Usage For the treatment of postoperative inflammation in patients who have undergone cataract extraction.
Marketing Status approved
ATC Code S01BC11
DrugBank ID DB00963
KEGG ID D07541
MeSH ID C053083
PubChem ID 60726
TTD Drug ID D0U1OM
NDC Product Code 65862-789; 49708-754; 68083-313; 50383-249; 72266-142
UNII 864P0921DW
Synonyms bromfenac | ISV-303 | Duract | sodium bromfenac | bromfenac sodium | Xibrom | AHR-10282
Chemical Information
Molecular Formula C15H12BrNO3
CAS Registry Number 91714-94-2
SMILES C1=CC(=C(C(=C1)C(=O)C2=CC=C(C=C2)Br)N)CC(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal sensation in eye06.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Blepharitis23.03.04.012; 06.04.04.0010.001841%Not Available
Burning sensation08.01.09.029; 17.02.06.0010.000921%Not Available
Corneal epithelium defect06.06.03.0120.000271%Not Available
Corneal erosion06.06.03.0030.000271%Not Available
Corneal infiltrates06.08.01.002--Not Available
Corneal oedema06.04.02.001--Not Available
Corneal perforation06.06.03.006; 12.01.04.003--Not Available
Corneal scar12.01.04.015; 06.06.03.015--Not Available
Cough22.02.03.001--
Dermatitis allergic10.01.03.014; 23.03.04.0030.001841%Not Available
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.0030.000921%Not Available
Drug hypersensitivity10.01.01.0010.000596%Not Available
Epistaxis24.07.01.005; 22.04.03.001--
Eye discharge06.04.05.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye irritation06.04.05.0030.004603%Not Available
Eye pain06.08.03.0020.000921%
Eye swelling06.08.03.0030.000921%Not Available
Headache17.14.01.001--
Iritis10.02.01.022; 06.04.03.002--Not Available
Keratitis06.04.02.0020.000271%
Mydriasis17.02.11.003; 06.05.03.0040.000271%Not Available
Ocular hyperaemia06.04.05.0040.000921%Not Available
Pain08.01.08.004--
Photophobia17.17.02.006; 06.01.01.004--
Punctate keratitis06.04.02.0030.000271%Not Available
Retinal disorder06.08.03.005--Not Available
Retinal exudates14.07.01.007; 05.07.01.007; 24.03.07.007; 06.10.02.003--Not Available
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