| Pharmaceutical Information |
| Drug Name |
Bromhexine |
| Drug ID |
BADD_D00302 |
| Description |
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as an over-the-counter drug in many countries.[A233240] Recently, bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of COVID-19 due to their interactions with cell receptors in the lungs.[A233345,A233370] |
| Indications and Usage |
Bromohexine is used alone or with other ingredients such as [diphenhydramine], [dextromethorphan], and [guaifenesin] to reduce mucus viscosity and clear mucus in conditions associated with mucus hypersecretion, including the common cold, influenza, respiratory tract infections, or other conditions.[L29975,L24819,L33060] |
| Marketing Status |
approved |
| ATC Code |
R05CB02 |
| DrugBank ID |
DB09019
|
| KEGG ID |
D07542
|
| MeSH ID |
D001964
|
| PubChem ID |
2442
|
| TTD Drug ID |
D07UWJ
|
| NDC Product Code |
Not Available |
| UNII |
Q1J152VB1P
|
| Synonyms |
Bromhexine | Aparsonin | Bromhexin BC | BC, Bromhexin | Bromhexin Berlin-Chemie | Bromhexin Berlin Chemie | Bromhexin BerlinChemie | Bromhexine Hydrochloride | Hydrochloride, Bromhexine | Bromhexine Monohydrochloride | Monohydrochloride, Bromhexine | Brotussol | bromhexin von ct | ct, bromhexin von | von ct, bromhexin | Darolan | Dur-Elix | Dur Elix | DurElix | Famel Bromhexine | Bromhexine, Famel | Flegamin | Flubron | Hustentabs-ratiopharm | Hustentabs ratiopharm | Hustentabsratiopharm | Bromhexin-ratiopharm | Bromhexin ratiopharm | Bromhexinratiopharm | Mucohexine | NA-274 | NA 274 | NA274 | Tesacof | Bisolvon | Quentan | Bromhexin |
|
| Chemical Information |
| Molecular Formula |
C14H20Br2N2 |
| CAS Registry Number |
3572-43-8 |
| SMILES |
CN(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2 |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
