Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood immunoglobulin E increased13.06.05.0030.000406%Not Available
Coeliac disease14.02.01.007; 10.04.04.012; 07.17.01.0080.000609%Not Available
Gastroenteritis Escherichia coli11.02.10.005; 07.19.03.0150.000609%Not Available
Ileal stenosis07.13.06.0060.001016%
JC virus infection11.05.05.0030.000159%Not Available
Persecutory delusion19.10.01.0070.000609%Not Available
Pouchitis12.02.03.022; 07.08.03.0170.000406%Not Available
Renal amyloidosis20.05.03.019; 10.02.05.0050.000609%Not Available
Seminoma16.25.03.002; 21.13.02.0040.000609%Not Available
Small for dates baby18.04.02.0020.000813%Not Available
Spinal column stenosis17.10.01.011; 15.10.04.0030.000406%Not Available
Pneumococcal sepsis11.02.06.0070.000159%Not Available
Clostridium difficile infection11.02.02.0090.000813%Not Available
Infective exacerbation of chronic obstructive airways disease11.01.09.015; 22.03.01.0220.000159%Not Available
Gastrointestinal oedema07.11.01.0120.000406%Not Available
Asthmatic crisis22.03.01.0180.000609%Not Available
Stress cardiomyopathy24.04.04.026; 02.04.01.0120.000406%Not Available
Herpes zoster cutaneous disseminated23.09.03.013; 11.05.02.0270.000406%Not Available
Aspirin-exacerbated respiratory disease22.03.01.021; 10.01.01.0280.000406%Not Available
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