Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Failure to thrive19.07.05.001; 18.04.01.003; 14.03.02.0080.000689%Not Available
Fat tissue increased08.01.03.0090.000406%Not Available
Fatigue08.01.01.002--
Feeling abnormal08.01.09.0140.001625%Not Available
Feeling hot08.01.09.0090.000609%Not Available
Fistula15.03.02.0010.000813%Not Available
Flatulence07.01.04.002--
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Flushing24.03.01.002; 23.06.05.003; 08.01.03.0250.000813%
Fracture12.04.02.001; 15.08.02.001--
Gait disturbance17.02.05.016; 08.01.02.002--
Gastric haemorrhage24.07.02.007; 07.12.01.0010.000406%
Gastrointestinal fistula07.11.05.001--
Gastrooesophageal reflux disease07.02.02.0030.000609%
Gastroenteritis11.01.07.004; 07.19.03.001--Not Available
Gastrointestinal disorder07.11.01.0010.001016%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.005--
Glaucoma06.03.01.002--
Glomerulonephritis membranous20.05.01.0070.000406%Not Available
Glossitis07.14.01.001--Not Available
Gravitational oedema08.01.07.005; 02.05.04.014--Not Available
Haematuria24.07.01.047; 20.02.01.006--
Haemoglobin13.01.05.018--Not Available
Haemorrhoids07.15.03.001; 24.10.02.002--
Hair growth abnormal23.02.06.006--Not Available
Hallucination19.10.02.0020.000813%
Headache17.14.01.001--
Heart rate increased13.14.04.0020.002031%Not Available
Henoch-Schonlein purpura10.02.02.004; 01.01.04.001; 24.07.06.003; 23.06.01.0020.000406%Not Available
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