Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Bumetanide
Drug ID BADD_D00307
Description Bumetanide is a sulfamyl diuretic.
Indications and Usage For the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
Marketing Status approved
ATC Code C03CA02
DrugBank ID DB00887
KEGG ID D00247
MeSH ID D002034
PubChem ID 2471
TTD Drug ID D0R7HO
NDC Product Code 0832-0541; 60468-001; 72643-030; 0185-0129; 0641-6161; 0904-7016; 14501-0036; 17337-0055; 0185-0130; 50090-6137; 60687-535; 65219-570; 68382-526; 70518-3191; 71335-1692; 0641-6008; 17337-0011; 14539-702; 43353-288; 0185-0128; 50090-5666; 50090-6139; 50090-6345; 69238-1489; 70771-1025; 55154-4345; 65219-572; 68382-527; 69238-1491; 70518-2678; 72205-101; 0641-6162; 0832-0542; 55154-4733; 68462-469; 68462-470; 70860-405; 70860-406; 0615-8393; 0832-0540; 57755-0004; 63190-0370; 63190-0430; 42799-121; 50090-5068; 50090-5664; 70771-1026; 42799-120; 50090-5064; 50090-6138; 50268-132; 68083-497; 0409-1412; 14539-700; 50090-5663; 63629-4968; 68083-496; 72572-040; 72572-041; 60468-003; 42799-119; 50090-6308; 60687-384; 70771-1024; 72205-102; 0615-8394; 60468-002; 14539-701; 43353-292; 50090-6304; 50268-130; 50268-131; 55154-3572; 68382-525; 69238-1490; 0641-6007; 51662-1449
UNII 0Y2S3XUQ5H
Synonyms Bumetanide | Bumethanide | Bumex | PF-1593 | PF 1593 | PF1593 | Drenural | Fordiuran | Miccil | Bumedyl | Burinex
Chemical Information
Molecular Formula C17H20N2O5S
CAS Registry Number 28395-03-1
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Electrolyte imbalance14.05.01.002--Not Available
Encephalopathy17.13.02.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Fatigue08.01.01.002--
Gastrointestinal pain07.01.05.005--
Glycosuria20.02.01.005--
Glucose urine present13.13.02.001--Not Available
Gynaecomastia21.05.04.003; 05.05.02.003--
Haematocrit13.01.05.017--Not Available
Haemoglobin abnormal13.01.05.011--Not Available
Headache17.14.01.001--
Hepatocellular injury09.01.07.008--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkalaemia14.05.03.0010.000282%
Hyperuricaemia14.09.01.003--
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypervolaemia02.05.04.019; 14.05.06.0030.000424%Not Available
Hypochloraemia14.05.08.003--Not Available
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.0010.000565%
Hyponatraemia14.05.04.0020.000282%
Hypotension24.06.03.0020.001328%
Hypovolaemia14.05.05.0020.000282%Not Available
Leukopenia01.02.02.001--Not Available
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.000282%Not Available
Malaise08.01.01.0030.000282%
Metabolic alkalosis14.01.02.0040.000282%Not Available
Muscle spasms15.05.03.0040.006526%
Muscular weakness17.05.03.005; 15.05.06.0010.000621%
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