Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Carbenicillin
Drug ID BADD_D00357
Description Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Indications and Usage For the treatment of acute and chronic infections of the upper and lower urinary tract and in asymptomatic bacteriuria due to susceptible strains of bacteria.
Marketing Status approved; investigational
ATC Code J01CA03
DrugBank ID DB00578
KEGG ID D07614
MeSH ID D002228
PubChem ID 20824
TTD Drug ID D02TBI
NDC Product Code Not Available
UNII G42ZU72N5G
Synonyms Carbenicillin | Carboxybenzyl Penicillin | Penicillin, Carboxybenzyl | Carbapen | Pyopen | Carbenicillin Disodium | Disodium, Carbenicillin | Geopen | Microcillin | Anabactyl | Carbecin
Chemical Information
Molecular Formula C17H18N2O6S
CAS Registry Number 4697-36-3
SMILES CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)C(=O)O)C(=O)O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaemia01.03.02.001--
Body temperature increased13.15.01.001--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Eosinophilia01.02.04.001--
Flatulence07.01.04.002--
Glossitis07.14.01.001--Not Available
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Leukopenia01.02.02.001--Not Available
Nausea07.01.07.001--
Neutropenia01.02.03.004--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Thrombocytopenia01.08.01.002--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vaginal infection11.01.10.002; 21.14.02.002--
Vomiting07.01.07.003--
Eye pruritus06.04.05.006--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Vulvovaginal inflammation21.14.02.014--Not Available
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