Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Carbimazole
Drug ID BADD_D00360
Description An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Indications and Usage For the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
Marketing Status approved; investigational
ATC Code H03BB01
DrugBank ID DB00389
KEGG ID D07616
MeSH ID D002231
PubChem ID 31072
TTD Drug ID D02CKX
NDC Product Code Not Available
UNII 8KQ660G60G
Synonyms Carbimazole | Carbimazole Henning | Neo-Thyreostat | Neomercazole | Neo-Mercazole | Neo Tomizol
Chemical Information
Molecular Formula C7H10N2O2S
CAS Registry Number 22232-54-8
SMILES CCOC(=O)N1C=CN(C1=S)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.004--Not Available
Pancytopenia01.03.03.003--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Skin disorder23.03.03.007--Not Available
Stomatitis07.05.06.005--
Thrombocytopenia01.08.01.002--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Emotional distress19.04.02.008--Not Available
Contusion15.03.05.007; 24.07.06.001; 23.03.11.002; 12.01.06.001--
Lymphatic disorder01.09.01.003--Not Available
Foetor hepaticus09.01.05.006; 07.01.06.026--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Haemorrhage24.07.01.002--Not Available
Angiopathy24.03.02.007--Not Available
Ill-defined disorder08.01.03.049--Not Available
Blood disorder01.05.01.004--Not Available
Bone marrow failure01.03.03.005--
Oropharyngeal discomfort22.12.03.015; 07.05.05.008--Not Available
Oropharyngeal pain22.12.03.016; 07.05.05.004--
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