Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ceftaroline fosamil
Drug ID BADD_D00398
Description Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria: Acute bacterial skin and skin structure infections. Community-acquired bacterial pneumonia.
Indications and Usage Ceftaroline fosamil is indicated for the treatment of patients with the following infections caused by susceptible isolates of the designated microorganisms.
Marketing Status approved; investigational
ATC Code J01DI02
DrugBank ID DB06590
KEGG ID D08884
MeSH ID C515501
PubChem ID 9852981
TTD Drug ID Not Available
NDC Product Code 0456-0400; 0456-0600
UNII 7P6FQA5D21
Synonyms ceftaroline fosamil | Teflaro | TAK-599 | TAK599 | PPI-0903 | PPI0903
Chemical Information
Molecular Formula C22H21N8O8PS4
CAS Registry Number 229016-73-3
SMILES CCON=C(C1=NSC(=N1)NP(=O)(O)O)C(=O)NC2C3N(C2=O)C(=C(CS3)SC4=NC(=CS4)C5=CC=[N+](C= C5)C)C(=O)[O-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypervolaemia02.05.04.019; 14.05.06.0030.000049%Not Available
Hypokalaemia14.05.03.002--
Immune system disorder10.02.01.001--Not Available
Leukopenia01.02.02.0010.000049%Not Available
Nausea07.01.07.0010.000379%
Nephropathy toxic20.05.03.002; 12.03.01.0100.000107%Not Available
Nervous system disorder17.02.10.001--Not Available
Neutropenia01.02.03.0040.000612%Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.0100.000165%
Palpitations02.11.04.012--
Pancytopenia01.03.03.0030.000097%Not Available
Phlebitis24.12.03.004; 12.02.01.002--
Pruritus23.03.12.0010.000544%
Pyrexia08.05.02.0030.000097%
Rash23.03.13.0010.000782%Not Available
Renal failure20.01.03.0050.000097%Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.000107%
Seizure17.12.03.0010.000049%
Skin disorder23.03.03.007--Not Available
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.0050.000049%
Swelling face08.01.03.100; 23.04.01.018; 10.01.05.018--Not Available
Thrombocytopenia01.08.01.0020.000131%Not Available
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urticaria23.04.02.001; 10.01.06.0010.000190%
Vomiting07.01.07.0030.000379%
Mental status changes19.07.01.0010.000049%Not Available
Peripheral swelling08.01.03.053; 02.05.04.0150.000107%Not Available
Lymphatic disorder01.09.01.003--Not Available
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