Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ceftizoxime sodium
Drug ID BADD_D00403
Description A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders.
Indications and Usage Cetizoxime was previously indicated for the treatment of infections due to susceptible strains of bacteria.
Marketing Status approved; withdrawn
ATC Code J01DD07
DrugBank ID DB01332
KEGG ID D00923
MeSH ID D015296
PubChem ID 23663938
TTD Drug ID D0Y7BD
NDC Product Code Not Available
UNII 26337D5X88
Synonyms Ceftizoxime | Ceftizoxime Sodium | Sodium, Ceftizoxime | Ceftizoxime Monosodium Salt | Monosodium Salt, Ceftizoxime | Salt, Ceftizoxime Monosodium | SKF-88373 | SKF 88373 | SKF88373 | FR-13749 | FR 13749 | FR13749 | SK&F 88373-2 | SK&F 88373 2 | SK&F 883732 | Cefizox | FK749 | FK-749 | FK 749
Chemical Information
Molecular Formula C13H12N5NaO5S2
CAS Registry Number 68401-82-1
SMILES CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=CCS3)C(=O)[O-].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Serum sickness-like reaction10.01.03.005; 08.01.03.003--Not Available
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Tenderness08.01.08.005--Not Available
Thrombocytopenia01.08.01.002--Not Available
Thrombocytosis01.08.02.001--Not Available
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Vaginal infection21.14.02.002; 11.01.10.002--
Vomiting07.01.07.003--
Haemorrhage24.07.01.002--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Induration08.01.03.020--Not Available
Coombs test positive13.01.01.002--Not Available
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