| Drug Name |
Ceftriaxone sodium |
| Drug ID |
BADD_D00406 |
| Description |
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic.[A215582] It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges[A215582], eyes[A215647], and inner ear[A215627]. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or twice-daily dosing.[A215582] |
| Indications and Usage |
Ceftriaxone is used for the treatment of the infections (respiratory, skin, soft tissue, UTI, ENT) caused by susceptible organisms.[L15082] Organisms that are generally susceptible to ceftriaxone include S. pneumoniae, S. pyogenes (group A beta-hemolytic streptococci), coagulase-negative staphylococci, Some Enterobacter spp, H. influenzae, N. gonorrhoeae, P. mirabilis, E. coli, Klebsiella spp, M. catarrhalis, B. burgdorferi, and some oral anaerobes.[A215582] |
| Marketing Status |
approved |
| ATC Code |
J01DD04 |
| DrugBank ID |
DB01212
|
| KEGG ID |
D00924
|
| MeSH ID |
D002443
|
| PubChem ID |
9570985
|
| TTD Drug ID |
D07ACT
|
| NDC Product Code |
67184-1006; 0409-7333; 0409-7337; 70518-2301; 71205-545; 0781-3208; 66288-6100; 67184-1005; 0409-7334; 71205-710; 60505-6148; 0338-5003; 70518-0659; 0409-7332; 0409-7335; 0409-7338; 0781-3206; 60505-6149; 0781-3210; 60505-6152; 0338-5002; 0781-3207; 51065-004; 50090-0944; 60505-6151; 0781-3209; 25021-108; 50090-3838; 60505-6150; 67184-1007; 67184-1008; 0409-7336; 70518-2499; 50090-4689 |
| UNII |
023Z5BR09K
|
| Synonyms |
Ceftriaxone | Ceftriaxon | Cefatriaxone | Ceftriaxone, Disodium Salt, Hemiheptahydrate | Ceftrex | Ceftriaxon Curamed | Ceftriaxon Hexal | Ceftriaxona Andreu | Ceftriaxona LDP Torlan | Ceftriaxone Irex | Ceftriaxone Sodium | Ceftriaxone Sodium, Anhydrous | Anhydrous Ceftriaxone Sodium | Lendacin | Longacef | Longaceph | Ro13-9904 | Ro13 9904 | Ro139904 | Ro-13-9904 | Ro 13-9904 | Ro 13 9904 | Ro 139904 | Rocephin | Rocefalin | Rocephine | Rocefin | Tacex | Terbac | Ceftriaxone, Disodium Salt | Benaxona | Cefaxona |
