Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cetylpyridinium chloride
Drug ID BADD_D00423
Description Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Indications and Usage Typically employed as the cetylpyridinium chloride salt, this compound is commonly used as an active ingredient in various over-the-counter mouthwashes, toothpastes, lozenges, and mouth sprays where it is generally indicated for antiseptic actions, gingivitis and plaque prevention, as well as action or prevention against some other oropharyngeal bacterial infections [A24813, L2754, L2755].
Marketing Status approved
ATC Code R02AA06; D08AJ03; B05CA01; D09AA07
DrugBank ID DB11073
KEGG ID D01062
MeSH ID D002594
PubChem ID 31239
TTD Drug ID Not Available
NDC Product Code 76357-250; 10237-259; 72751-2302; 21130-299; 30142-299; 35000-889; 36800-299; 37000-451; 53462-175; 55882-6200; 63148-553; 63645-179; 86157-0004; 25119-0256; 24765-134; 35000-891; 41163-299; 46994-299; 50804-299; 67091-105; 69423-864; 69423-906; 10237-258; 35000-723; 35000-735; 37000-576; 37000-843; 37808-509; 54473-294; 64854-014; 66923-002; 69423-863; 56062-299; 64854-012; 69423-939; 33992-0299; 35000-720; 35000-890; 37012-299; 59779-299; 69423-856; 69423-893; 72551-247; 37000-480; 41250-826; 51414-105; 53462-375; 35000-892; 53329-030; 55301-299; 63824-790; 63940-299; 69423-858; 76357-285; 11822-5761; 37000-452; 37000-976; 41520-299; 63941-299; 67933-0321; 69423-855; 69423-931; 72288-299; 76357-211; 76357-230; 76357-255; 76670-0012; 76670-0015; 0869-0299; 37000-949; 53942-299; 59450-997; 76357-210; 35000-390; 0135-0650; 49035-299; 55316-942; 58578-0407; 63148-010; 67751-186; 69196-3001; 69423-905; 49452-1890; 11673-299; 35000-731; 37000-479; 0135-0651; 53462-275; 55319-299; 55910-299
UNII D9OM4SK49P
Synonyms Cetylpyridinium | Hexadecylpyridinium | Cetylpyridium | Biosept | Ceepryn Chloride | Chloride, Ceepryn | Cetamium | Catamium | Cetylpyridinium Chloride | Chloride, Cetylpyridinium | Sterogenol | Dobendan | Merocets | Pristacin | Cetylpyridinium Chloride Anhydrous | Anhydrous, Cetylpyridinium Chloride | Chloride Anhydrous, Cetylpyridinium | Pyrisept | Angifonil | Cetylyre
Chemical Information
Molecular Formula C21H38ClN
CAS Registry Number 123-03-5
SMILES CCCCCCCCCCCCCCCC[N+]1=CC=CC=C1.[Cl-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Erythema23.03.06.001--Not Available
Gingival pain07.09.13.010--
Gingival swelling07.09.13.013--Not Available
Gingivitis07.09.10.002; 11.01.04.013--
Gingival abscess11.01.04.011; 07.09.10.001--Not Available
Haemorrhage24.07.01.002--Not Available
Loose tooth07.09.05.009--Not Available
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