Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cevimeline
Drug ID BADD_D00424
Description Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Indications and Usage For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Marketing Status approved
ATC Code N07AX03
DrugBank ID DB00185
KEGG ID D07667
MeSH ID C059240
PubChem ID 2684
TTD Drug ID D0Q4CS
NDC Product Code 64642-011; 63304-479
UNII K9V0CDQ56E
Synonyms cevimeline | 2-methyspiro(1,3-oxathiolane-5,3)quinuclidine | AF 102B, (trans)-isomer | AF-102B | AF 102B | AF102B | Evoxac | FKS 508 | FKS-508 | SNI 2011 | SNI-2011 | AF 102B, (cis-(+))-isomer | cevimeline hydrochloride
Chemical Information
Molecular Formula C10H17NOS
CAS Registry Number 124620-88-8
SMILES CC1OC2(CN3CCC2CC3)CS1
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Chest pain22.12.02.003; 02.02.02.011; 08.01.08.002--Not Available
Chills08.01.09.001; 15.05.03.016--
Choking22.12.03.003--Not Available
Cholecystitis09.03.01.001--
Cholelithiasis09.03.01.002--Not Available
Cholinergic syndrome17.05.01.002--Not Available
Chronic obstructive pulmonary disease22.03.01.007--Not Available
Cold sweat23.02.03.002; 08.01.03.024--Not Available
Colitis07.08.01.001--
Colitis ulcerative10.02.01.004; 07.08.01.005--Not Available
Coma17.02.09.001--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis11.01.06.012; 06.04.01.002--
Constipation07.02.02.001--
Coordination abnormal17.02.02.004--Not Available
Corneal opacity06.06.03.005--Not Available
Costochondritis15.07.03.001--Not Available
Cough22.02.03.001--
Crying08.01.03.005; 19.04.02.002; 17.02.05.013; 12.02.11.001--Not Available
Cystitis20.03.02.002; 11.01.14.001--
Deafness04.02.01.001--Not Available
Dehydration14.05.05.0010.015547%
Delirium19.13.02.001--
Delusion19.10.01.001--
Dementia19.20.02.001; 17.03.01.001--Not Available
Dental caries07.09.01.001--
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis bullous23.03.01.002--
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003--Not Available
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