Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorphenamine
Drug ID BADD_D00444
Description A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Indications and Usage For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever.
Marketing Status approved
ATC Code R06AB04
DrugBank ID DB01114
KEGG ID D07398
MeSH ID D002744
PubChem ID 2725
TTD Drug ID D0B7NG
NDC Product Code Not Available
UNII 3U6IO1965U
Synonyms Chlorpheniramine | Chlorprophenpyridamine | Chlorphenamine | Aller-Chlor | Antihistaminico Llorens | Chlor-100 | Chlor-Trimeton | Cloro-Trimeton | Chlorpheniramine Maleate | Maleate, Chlorpheniramine | Chlorpheniramine Tannate | Tannate, Chlorpheniramine | Chlorpro | Chlorspan 12 | Chlortab-4 | Efidac 24 | Kloromin | Piriton | Teldrin | Chlo-Amine | Chlor-Tripolon
Chemical Information
Molecular Formula C16H19ClN2
CAS Registry Number 113-92-8
SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypoplastic anaemia01.03.03.006--Not Available
Hyporeflexia17.02.01.003--
Hypotension24.06.03.002--
Injection site inflammation12.07.03.009; 08.02.03.008--Not Available
Injection site reaction12.07.03.015; 08.02.03.014--
Insomnia19.02.01.002; 17.15.03.002--
Irritability19.04.02.013; 08.01.03.011--
Labyrinthitis11.01.05.002; 04.04.03.001--Not Available
Mental disability26.01.01.001--Not Available
Mental impairment19.21.02.003; 17.03.03.002--Not Available
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nasal congestion22.04.04.001--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neuritis17.09.03.001--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema mouth23.04.01.008; 10.01.05.006; 07.05.04.001--Not Available
Oedema peripheral02.05.04.007; 14.05.06.011; 08.01.07.007--
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
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