Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Chlorzoxazone
Drug ID BADD_D00449
Description A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Indications and Usage For the relief of discomfort associated with acute painful musculoskeletal conditions.
Marketing Status approved
ATC Code M03BB03
DrugBank ID DB00356
KEGG ID D00771
MeSH ID D002753
PubChem ID 2733
TTD Drug ID D08ZEB
NDC Product Code 13811-717; 16571-726; 0254-2053; 42494-426; 0254-2005; 53002-5760; 55700-951; 60760-479; 69499-330; 59651-306; 50090-0315; 55289-633; 71335-2009; 63629-1586; 70954-085; 71205-711; 72319-168; 0591-2520; 46016-9522; 58159-030; 76055-0034; 45865-434; 80425-0315; 70966-0019; 68025-046; 16571-725; 42494-425; 52817-230; 61919-478; 68025-047; 72319-169; 60760-619; 63629-9158; 43235-0005; 52817-231; 60760-578; 71335-1914; 51862-339; 63187-317; 54871-0001; 13811-718; 16571-727; 24470-923; 42494-428
UNII H0DE420U8G
Synonyms Chlorzoxazone | Parafon | Parafon Forte DSC | Paraflex
Chemical Information
Molecular Formula C7H4ClNO2
CAS Registry Number 95-25-0
SMILES C1=CC2=C(C=C1Cl)NC(=O)O2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Anaphylactic reaction24.06.03.006; 10.01.07.001--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Chromaturia20.02.01.002--
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dyspepsia07.01.02.001--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Feeling abnormal08.01.09.014--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Malaise08.01.01.003--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Rash23.03.13.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Ill-defined disorder08.01.03.049--Not Available
Device stimulation issue27.01.02.005--Not Available
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