| Pharmaceutical Information |
| Drug Name |
Cholestyramine resin |
| Drug ID |
BADD_D00452 |
| Description |
Cholestyramine or colestyramine is a bile acid sequestrant. Bile acid sequestrants are polymeric compounds which serve as ion exchange resins. Cholestyramine resin is quite hydrophilic, but insoluble in water. |
| Indications and Usage |
Indicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction. |
| Marketing Status |
approved; investigational |
| ATC Code |
C10AC01 |
| DrugBank ID |
DB01432
|
| KEGG ID |
D02690
|
| MeSH ID |
D002792
|
| PubChem ID |
137699107
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
38779-0822; 62991-2650; 55363-454; 51552-0684; 49452-2011 |
| UNII |
4B33BGI082
|
| Synonyms |
Cholestyramine Resin | Cholestyramine Resins | Resin, Cholestyramine | Resins, Cholestyramine | Colestyramin | Colestyramins | Colestyramine | Colestyramines | Cholestyramine | Cholestyramines | MK-135 | MK 135 | MK135 | Questran | Questrans | Cuemid | Cuemids | Quantalan | Quantalans |
|
| Chemical Information |
| Molecular Formula |
C27H47ClN2 |
| CAS Registry Number |
11041-12-6 |
| SMILES |
CCC(C)C.CCC(CC(C)C1=CC=CC=C1)C2=CC=C(C=C2)C[N+](C)(C)C.N.[Cl-] |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
