| Pharmaceutical Information |
| Drug Name |
Cholic acid |
| Drug ID |
BADD_D00453 |
| Description |
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem]
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome). |
| Indications and Usage |
Oral cholic acid is indicated for: treatment of bile acid synthesis disorders due to single enzyme defects; and as adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea or complications from decreased fat soluble vitamin absorption. |
| Marketing Status |
approved |
| ATC Code |
A05AA03 |
| DrugBank ID |
DB02659
|
| KEGG ID |
D10699
|
| MeSH ID |
D019826
|
| PubChem ID |
221493
|
| TTD Drug ID |
D0OR2L
|
| NDC Product Code |
45043-002; 45043-001; 47049-002; 47049-001 |
| UNII |
G1JO7801AE
|
| Synonyms |
Cholic Acid | Cholbam |
|
| Chemical Information |
| Molecular Formula |
C24H40O5 |
| CAS Registry Number |
81-25-4 |
| SMILES |
CC(CCC(=O)O)C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C |
| Chemical Structure |
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| ADRs Induced by Drug |
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