Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Choline magnesium trisalicylate
Drug ID BADD_D00456
Description Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Indications and Usage Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB01401
KEGG ID D07694
MeSH ID C017959
PubChem ID 54682045
TTD Drug ID Not Available
NDC Product Code Not Available
UNII DJJ95FJP1H
Synonyms choline magnesium trisalicylate | Tricosal | Tegunor | Trilisate
Chemical Information
Molecular Formula C26H29MgNO10
CAS Registry Number 85169-11-5
SMILES C[N+](C)(C)CCO.C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1 )C(=O)O)[O-].[Mg+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain upper07.01.05.003--
Asthma22.03.01.002; 10.01.03.010--Not Available
Blood creatinine increased13.13.01.004--
Blood urea increased13.13.01.006--Not Available
Confusional state19.13.01.001; 17.02.03.005--
Constipation07.02.02.001--
Deafness04.02.01.001--Not Available
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Duodenal ulcer07.04.02.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Ecchymosis24.07.06.002; 23.06.01.001; 01.01.03.001--Not Available
Epistaxis22.04.03.001; 24.07.01.005--
Erythema multiforme23.03.01.003; 10.01.03.015--
Gastric ulcer07.04.03.002--
Gastrointestinal disorder07.11.01.001--Not Available
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010--Not Available
Oesophagitis07.08.05.001--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Tinnitus17.04.07.004; 04.04.01.002--
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
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