Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cinoxacin
Drug ID BADD_D00470
Description Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Indications and Usage For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: Escherichia coli, Proteus mirabilis, Proteus vulgaris, Klebsiella species (including K. pneumoniae), and Enterobacter species.
Marketing Status approved; investigational; withdrawn
ATC Code J01MB06
DrugBank ID DB00827
KEGG ID D00872
MeSH ID D002937
PubChem ID 2762
TTD Drug ID D07UXP
NDC Product Code Not Available
UNII LMK22VUH23
Synonyms Cinoxacin | Clinoxacin | Azolinic Acid | Acid, Azolinic | Compound 64716 | Cinobac
Chemical Information
Molecular Formula C12H10N2O5
CAS Registry Number 28657-80-9
SMILES CCN1C2=CC3=C(C=C2C(=O)C(=N1)C(=O)O)OCO3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Eosinophilia01.02.04.001--
Erythema multiforme10.01.03.015; 23.03.01.003--
Gastrointestinal pain07.01.05.005--
Headache17.14.01.001--
Hypersensitivity10.01.03.003--
Insomnia19.02.01.002; 17.15.03.002--
Nausea07.01.07.001--
Oedema08.01.07.006; 14.05.06.010--Not Available
Pain08.01.08.004--
Paraesthesia23.03.03.094; 17.02.06.005--
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome23.03.01.007; 12.03.01.014; 11.07.01.005; 10.01.01.045--
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.006--
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Decreased appetite08.01.09.028; 14.03.01.005--
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