Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pericardial disease02.06.01.006--Not Available
Abnormal behaviour19.01.01.0010.000061%Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Feeling of body temperature change08.01.09.012--Not Available
Erectile dysfunction21.03.01.007; 19.08.04.0010.000057%
Ill-defined disorder08.01.03.049--Not Available
Lacrimal disorder06.08.02.005--Not Available
Red blood cell abnormality01.07.02.006--Not Available
Blood disorder01.05.01.004--Not Available
Adverse drug reaction08.06.01.009--Not Available
Autonomic neuropathy17.05.01.009--Not Available
Disease recurrence08.01.03.0500.000042%Not Available
Psychotic disorder19.03.01.0020.000019%
Urine analysis abnormal13.13.02.008--Not Available
Unevaluable event08.01.03.0510.000103%Not Available
Increased bronchial secretion22.12.01.002--Not Available
Female sexual arousal disorder21.03.02.011; 19.08.04.0040.000019%Not Available
Cystitis noninfective20.03.02.001--
Osteonecrosis of jaw24.04.05.005; 15.02.04.0100.000029%
Suicidal behaviour19.12.01.0060.000038%Not Available
Gastrointestinal sounds abnormal07.01.01.0020.000019%Not Available
Anal pruritus07.03.03.002--Not Available
Anorectal discomfort07.03.03.003--Not Available
Genital hypoaesthesia17.02.06.028; 21.10.05.0120.000029%Not Available
Acute kidney injury20.01.03.016--
Reversible cerebral vasoconstriction syndrome24.04.06.026; 18.06.01.004; 17.08.02.014--Not Available
Candida infection11.03.03.021--
Anal incontinence07.01.06.029; 17.05.01.021--
Frustration tolerance decreased19.04.02.016--Not Available
Depersonalisation/derealisation disorder19.14.01.004--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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