Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bipolar II disorder19.16.01.005--Not Available
Carcinoid syndrome16.32.02.004; 05.08.02.0050.000019%Not Available
Dissociative amnesia19.14.01.0050.000019%Not Available
Grunting22.02.01.0300.000019%Not Available
Neonatal respiratory distress syndrome22.11.02.010; 18.04.10.0030.000095%Not Available
Obstructed labour18.07.01.0080.000019%Not Available
Tremor neonatal18.04.04.012; 17.01.06.0100.000019%Not Available
Vesicoureteric reflux20.03.05.0020.000038%Not Available
Hypertonia neonatal18.04.01.016; 17.05.02.017; 15.05.04.0190.000038%Not Available
Negative thoughts19.15.02.012--Not Available
Sopor17.02.04.021; 19.02.04.0020.000038%Not Available
Single functional kidney20.01.02.0190.000038%Not Available
Tachyphrenia17.03.03.007; 19.10.03.0100.000051%Not Available
Rectourethral fistula20.07.03.005; 12.02.10.009; 07.11.05.0170.000048%Not Available
Stiff person syndrome15.05.04.021; 10.04.10.017; 17.05.02.018--Not Available
Neonatal behavioural syndrome22.11.02.007; 18.04.04.010; 17.02.05.058; 15.05.04.020--Not Available
Pharyngeal paraesthesia17.02.06.035; 22.04.05.018--Not Available
Infantile apnoea22.11.02.004; 18.04.15.0030.000019%Not Available
Selective eating disorder19.09.01.012; 14.03.02.0240.000019%Not Available
Attention deficit hyperactivity disorder19.21.04.0040.000019%Not Available
Drug ineffective for unapproved indication12.09.02.002; 08.06.01.0380.000065%Not Available
Electric shock sensation17.02.07.024; 08.06.02.023--Not Available
Genital anaesthesia21.10.05.021; 17.02.06.042--Not Available
Heavy menstrual bleeding21.01.03.0050.000074%Not Available
Intermenstrual bleeding21.01.01.015--Not Available
Nasal flaring22.12.02.0080.000019%Not Available
Neonatal respiratory distress22.11.02.015; 18.04.10.004--Not Available
Sexually inappropriate behaviour19.05.01.0260.000042%Not Available
Therapeutic product effect decreased08.06.01.0500.000042%Not Available
Therapeutic response changed08.06.01.059--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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