Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperprolactinaemia05.03.01.002--Not Available
Hyperreflexia17.02.01.0020.000038%Not Available
Hypersensitivity10.01.03.0030.000924%
Hypersomnia19.02.05.001; 17.15.01.0010.000029%
Hypertension24.08.02.0010.000148%
Hypertonia17.05.02.001; 15.05.04.0070.000029%Not Available
Hypertrichosis23.02.04.002--
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypoaesthesia23.03.03.081; 17.02.06.0230.000084%Not Available
Hypochromic anaemia01.03.02.004--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.0010.000019%
Hypoglycaemia neonatal18.04.06.003; 14.06.03.006; 05.06.03.0060.000029%Not Available
Hypohidrosis23.02.03.005; 08.01.03.029--
Hypokalaemia14.05.03.0020.000029%
Hypokinesia17.01.02.0090.000019%Not Available
Hypomania19.16.02.001--Not Available
Hyponatraemia14.05.04.0020.000076%
Hypotension24.06.03.0020.000112%
Hypothyroidism05.02.03.001; 14.11.01.012--
Illusion19.10.05.0060.000019%Not Available
Immune system disorder10.02.01.001--Not Available
Impaired healing08.03.02.001--Not Available
Increased appetite14.03.01.003; 08.01.09.0270.000065%Not Available
Infection11.01.08.002--Not Available
Influenza like illness08.01.03.0100.000029%
Initial insomnia19.02.01.005; 17.15.03.0050.000029%Not Available
Injection site erythema23.03.06.015; 12.07.03.001; 08.02.03.0010.000129%Not Available
Injection site induration12.07.03.007; 08.02.03.0070.000194%Not Available
Injection site mass08.02.03.009; 12.07.03.0100.000129%Not Available
Injection site pain12.07.03.011; 08.02.03.0100.000171%Not Available
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ADReCS-Target
Drug Name ADR Term Target
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