| Pharmaceutical Information |
| Drug Name |
Clobetasol propionate |
| Drug ID |
BADD_D00490 |
| Description |
Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.[L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described in the literature in 1974.[A190936]
Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] |
| Indications and Usage |
Clobetasol propionate is indicated to treat moderate to severe plaque psoriasis[L11818,L118121,L11824] as well as inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.[L11815,L11827] |
| Marketing Status |
approved |
| ATC Code |
D07AD01 |
| DrugBank ID |
DB01013
|
| KEGG ID |
D01272
|
| MeSH ID |
D002990
|
| PubChem ID |
32798
|
| TTD Drug ID |
D0H0YD
|
| NDC Product Code |
79572-008; 42291-077; 50383-267; 51672-4193; 60429-902; 68071-2725; 0472-0403; 70771-1442; 52128-158; 16714-030; 0168-0163; 45802-437; 49502-537; 50383-269; 51672-1259; 62332-486; 63629-2393; 68382-998; 68462-529; 46439-8747; 33342-321; 43386-096; 50742-304; 51672-1258; 0299-3847; 62559-980; 63629-2395; 68462-532; 70700-106; 70710-1401; 71589-002; 0299-3849; 62332-707; 63646-500; 68180-956; 70710-1456; 71589-018; 22552-0006; 13668-569; 43538-952; 43538-953; 45802-925; 50090-5778; 50090-6402; 50383-978; 50383-979; 63629-2329; 63629-2392; 0378-8055; 68071-2764; 68788-8238; 70700-109; 71205-151; 72578-085; 51552-0605; 42571-362; 43538-950; 0168-0269; 50383-268; 51672-1293; 63629-2331; 63629-8637; 69238-1532; 71428-005; 0713-0656; 46439-8708; 49452-2141; 62991-1492; 42291-076; 63629-2332; 0591-4039; 43386-028; 0168-0162; 0168-0301; 50090-5079; 62332-465; 63629-2394; 63629-9461; 0378-8147; 68462-608; 70771-1209; 71085-007; 72189-262; 51927-2627; 40032-028; 0168-0293; 45802-637; 50090-5488; 51672-1350; 62332-548; 63629-2330; 63629-8639; 64980-441; 66993-939; 68180-536; 68462-530; 0472-0404; 70752-153; 70771-1080; 40032-096; 51672-1294; 51672-1371; 0299-3848; 62332-425; 62332-547; 63629-8638; 63629-9460; 68180-551; 68462-480; 68462-625; 69238-1732; 70771-1498; 64958-0101; 76003-0325; 16714-782; 45802-961; 50090-5264; 50383-266; 51672-1297; 51672-1347; 53002-9970 |
| UNII |
779619577M
|
| Synonyms |
Clobetasol | Clofenazon | Clobetasol Propionate | Clobetasol 17-Propionate | Clobetasol 17 Propionate | Clobex | Cormax | OLUX | Dermovate | Embeline | Embeline E | Temovate |
|
| Chemical Information |
| Molecular Formula |
C25H32ClFO5 |
| CAS Registry Number |
25122-46-7 |
| SMILES |
CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
