Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Clomiphene
Drug ID BADD_D00497
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D07726
MeSH ID D002996
PubChem ID 1548953
TTD Drug ID D0CT9Y
NDC Product Code Not Available
UNII 1HRS458QU2
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C26H28ClNO
CAS Registry Number 15690-57-0
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Leukaemia16.01.03.001; 01.10.03.001--
Leukocytosis01.02.01.002--
Limb reduction defect15.11.07.004; 03.11.07.004--Not Available
Liver disorder09.01.08.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Lymphocytic leukaemia16.01.09.001; 01.10.09.001--Not Available
Macular oedema06.04.06.005--Not Available
Malignant melanoma23.08.01.001; 16.03.01.001--Not Available
Meningomyelocele17.19.01.006; 03.10.02.006--Not Available
Menopausal symptoms21.02.02.002--Not Available
Mental disability26.01.01.001--Not Available
Microcephaly15.11.02.002; 03.11.02.002--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mood swings19.04.03.001--Not Available
Multiple pregnancy18.08.03.001--Not Available
Myalgia15.05.02.001--
Myopathy15.05.05.001--Not Available
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
Nervousness19.06.02.003--Not Available
Neurofibromatosis17.18.01.002; 16.09.01.002; 03.10.01.002; 23.05.01.018--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Optic neuritis10.02.01.097; 17.04.05.001; 06.04.08.002--Not Available
Ovarian cancer21.11.01.003; 16.12.04.001--Not Available
Ovarian cyst21.11.01.002; 16.04.03.001--Not Available
Ovarian enlargement21.11.02.001--Not Available
Ovarian germ cell teratoma benign21.11.01.004; 16.04.03.002--Not Available
Ovarian hyperstimulation syndrome05.05.01.013; 21.11.02.007--Not Available
Ovulation pain21.01.01.016--
Pain08.01.08.004--
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