Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Clomiphene citrate
Drug ID BADD_D00498
Description A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Indications and Usage Used mainly in female infertility due to anovulation (e.g. due to polycystic ovary syndrome) to induce ovulation.
Marketing Status approved; investigational
ATC Code G03GB02
DrugBank ID DB00882
KEGG ID D00962
MeSH ID D002996
PubChem ID 60974
TTD Drug ID D0I5WB
NDC Product Code 51927-0249; 73377-229; 49884-701; 50090-0678; 10577-916; 46014-1122; 51927-0056; 0713-0885; 73212-029; 63629-2165; 63629-5302; 63275-9964; 63629-9276; 48087-0025; 49169-1040; 51552-1580; 68071-2638; 73309-047; 50090-6500; 17369-817; 48087-0144; 62991-2702; 61919-375; 38779-0390; 43647-456; 71052-338; 90027-025
UNII 1B8447E7YI
Synonyms Clomiphene | Clomifene | Chloramiphene | Clomifen | Clomiphene Citrate | Citrate, Clomiphene | Clomiphene Hydrochloride | Hydrochloride, Clomiphene | Serophene | Gravosan | Klostilbegit | Clostilbegit | Clomid | Clomide | Dyneric
Chemical Information
Molecular Formula C32H36ClNO8
CAS Registry Number 50-41-9
SMILES CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O) O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dermatitis23.03.04.002--Not Available
Diaphragmatic hernia22.09.02.001; 07.16.01.002--Not Available
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.002--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dwarfism15.02.03.005; 05.03.02.002--Not Available
Dyspnoea22.02.01.004; 02.11.05.003--
Ear malformation04.06.02.001; 03.13.02.001--Not Available
Ectopic pregnancy18.02.02.002--Not Available
Endometrial cancer16.12.02.001; 21.07.02.002--Not Available
Endometriosis21.07.01.004--Not Available
Erythema23.03.06.001--Not Available
Erythema multiforme10.01.03.015; 23.03.01.003--
Erythema nodosum23.07.02.001; 10.02.01.020--Not Available
Exomphalos07.16.03.002; 03.04.07.001--Not Available
Eye pain06.08.03.002--
Fallot's tetralogy03.07.06.001; 02.08.01.002--Not Available
Fatigue08.01.01.002--
Fibrocystic breast disease21.05.04.018; 16.14.01.003--Not Available
Glioblastoma multiforme17.20.02.001; 16.30.02.001--Not Available
Hair texture abnormal23.02.06.004--
Headache17.14.01.001--
Hepatic adenoma16.06.01.002; 09.04.01.002--Not Available
Hepatitis09.01.07.004--Not Available
Hodgkin's disease16.31.01.001; 01.16.01.001--Not Available
Hydrocephalus17.07.01.001--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertrichosis23.02.04.002--
Hypertriglyceridaemia14.08.02.001--
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