Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Cloxacillin
Drug ID BADD_D00510
Description A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].
Indications and Usage Cloxacillin is indicated for the treatment of beta-hemolytic streptococcal, pneumococcal, and staphylococcal infections (including beta-lactamase producing organisms).[L33170]
Marketing Status approved; investigational; vet_approved
ATC Code J01CF02
DrugBank ID DB01147
KEGG ID D07733
MeSH ID D003023
PubChem ID 6098
TTD Drug ID D04KTZ
NDC Product Code Not Available
UNII O6X5QGC2VB
Synonyms Cloxacillin | Chloroxacillin | Syntarpen | Tegopen | Cloxacillin Sodium | Sodium, Cloxacillin | Sodium Cloxacillin | Cloxacillin, Sodium
Chemical Information
Molecular Formula C19H18ClN3O5S
CAS Registry Number 61-72-3
SMILES CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Haemolytic anaemia01.06.03.002--Not Available
Hepatitis09.01.07.004--Not Available
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Injection site reaction12.07.03.015; 08.02.03.014--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Jaundice cholestatic09.01.01.005--Not Available
Leukopenia01.02.02.001--Not Available
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.005--Not Available
Myalgia15.05.02.001--
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Nausea07.01.07.001--
Nephritis20.05.02.001--Not Available
Neutropenia01.02.03.004--Not Available
Oedema08.01.07.006; 14.05.06.010--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oral candidiasis11.03.03.004; 07.05.07.001--Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Paraesthesia17.02.06.005; 23.03.03.094--
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Phlebitis24.12.03.004; 12.02.01.002--
Pruritus23.03.12.001--
Pseudomembranous colitis11.02.02.002; 07.19.01.003--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rash macular23.03.13.003--Not Available
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