| Pharmaceutical Information |
| Drug Name |
Cocaine |
| Drug ID |
BADD_D00514 |
| Description |
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. |
| Indications and Usage |
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities. |
| Marketing Status |
approved; illicit |
| ATC Code |
N01BC01; R02AD03; S01HA01; S02DA02 |
| DrugBank ID |
DB00907
|
| KEGG ID |
D00110
|
| MeSH ID |
D003042
|
| PubChem ID |
446220
|
| TTD Drug ID |
D04XPW
|
| NDC Product Code |
Not Available |
| UNII |
I5Y540LHVR
|
| Synonyms |
Cocaine | Cocaine Hydrochloride | Hydrochloride, Cocaine | Cocaine HCl | HCl, Cocaine |
|
| Chemical Information |
| Molecular Formula |
C17H21NO4 |
| CAS Registry Number |
50-36-2 |
| SMILES |
CN1C2CCC1C(C(C2)OC(=O)C3=CC=CC=C3)C(=O)OC |
| Chemical Structure |
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| ADRs Induced by Drug |
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