| Drug Name |
Colchicine |
| Drug ID |
BADD_D00518 |
| Description |
First approved by the FDA in 1961, colchicine is an alkaloid drug commonly used in the management of gout, a condition associated with the painful deposition of urate crystals in the joints.[A183614,L8138] It is derived from a plant belonging to the Lily family, known as Colchicum autumnale, or "autumn crocus".[A183611] Other than its use in gout, colchicine has been approved for managing exacerbations of Familial Mediterranean Fever (FMF), a hereditary autoinflammatory condition.[A186320,L8141] |
| Indications and Usage |
Colchicine is indicated for the prophylaxis and treatment of gout flares. It is also indicated in Familial Mediterranean fever (FMF) in children and adults of 4 years of age and older. It is important to note that this medication is not a pain reliever to be used for other painful conditions. Consider analgesics for this purpose.[L8138] Some off-label uses of colchicine include the treatment of the manifestations of Behcet's syndrome, pericarditis, and postpericardiotomy syndrome.[A183932,A183935] |
| Marketing Status |
approved |
| ATC Code |
M04AC01 |
| DrugBank ID |
DB01394
|
| KEGG ID |
D00570
|
| MeSH ID |
D003078
|
| PubChem ID |
6167
|
| TTD Drug ID |
D09DHY
|
| NDC Product Code |
0904-6732; 72643-009; 59467-318; 59651-455; 65162-710; 69037-0011; 0254-2008; 0378-1086; 51927-0277; 31722-899; 51407-082; 63187-292; 63629-7422; 63629-8362; 72189-249; 72189-331; 60687-389; 60687-727; 63629-2166; 67877-589; 70771-1590; 71205-310; 47234-0119; 50268-187; 64764-119; 70710-1571; 0591-2562; 71610-494; 75854-801; 61281-3600; 68404-0001; 23155-855; 64380-796; 70771-1396; 71335-1802; 0904-7120; 55742-127; 16714-039; 70010-002; 71205-687; 71335-1738; 63629-8766; 17359-5000; 66064-1008; 71335-1695; 43598-372; 49884-171; 50090-3465; 60687-358; 63629-2167; 70710-1351; 0143-3018; 42292-054 |
| UNII |
SML2Y3J35T
|
| Synonyms |
Colchicine | Colchicine, (R)-Isomer | Colchicine, (+-)-Isomer |
