| Pharmaceutical Information |
| Drug Name |
Colistimethate sodium |
| Drug ID |
BADD_D00524 |
| Description |
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa. |
| Indications and Usage |
For the treatment of acute or chronic infections due to sensitive strains of certain gram-negative bacilli, particularly _Pseudomonas aeruginosa_. |
| Marketing Status |
approved; vet_approved |
| ATC Code |
Not Available |
| DrugBank ID |
DB01111
|
| KEGG ID |
D02049
|
| MeSH ID |
C004691
|
| PubChem ID |
216258
|
| TTD Drug ID |
D0Q3BV
|
| NDC Product Code |
24507-005; 63323-393; 42023-131; 63552-010; 23155-193; 45932-0016; 45932-0053; 70594-023; 14789-201; 42513-0007; 45932-0015 |
| UNII |
XW0E5YS77G
|
| Synonyms |
colistinmethanesulfonic acid | colistimethate | colistimethate sodium | colistin sodium methanesulfonate | colistimethate, disodium salt |
|
| Chemical Information |
| Molecular Formula |
C58H105N16Na5O28S5 |
| CAS Registry Number |
12705-41-8 |
| SMILES |
CCC(C)CCCCC(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)[O-])C(=O
)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCNCS(=O)(=O)[O-])CC
(C)C)CC(C)C)CCNCS(=O)(=O)[O-])CCNCS(=O)(=O)[O-])C(C)O.[Na+].[Na+].[Na+].[Na+].[N
a+] |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
