| Drug Name |
Cyclophosphamide |
| Drug ID |
BADD_D00549 |
| Description |
Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide. It has been used in the treatment of lymphoma and leukemia. Its side effect, alopecia, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. |
| Indications and Usage |
Cyclophosphamide is indicated for the treatment of malignant lymphomas, multiple myeloma, leukemias, mycosis fungoides (advanced disease), neuroblastoma (disseminated disease), adenocarcinoma of the ovary, retinoblastoma, and carcinoma of the breast. It is also indicated for the treatment of biopsy-proven minimal change nephrotic syndrome in pediatric patients. |
| Marketing Status |
approved; investigational |
| ATC Code |
L01AA01 |
| DrugBank ID |
DB00531
|
| KEGG ID |
D00287; D07760
|
| MeSH ID |
D003520
|
| PubChem ID |
2907
|
| TTD Drug ID |
D0CT9C
|
| NDC Product Code |
14335-360; 38779-0506; 10019-944; 10019-945; 10019-984; 58623-0024; 62559-931; 70121-1240; 0781-3233; 0781-3244; 10019-955; 51927-4871; 71052-223; 81955-0004; 43598-662; 50742-520; 69097-517; 70121-1239; 72572-085; 72572-087; 0781-3255; 10019-935; 10019-942; 51927-0221; 76339-191; 62332-619; 70121-1238; 54879-022; 55150-271; 62332-618; 69097-516; 70860-218; 42973-318; 10019-937; 76339-164; 50742-519; 51407-748; 72603-411; 10019-939; 65124-0003; 50742-521; 54879-021; 68001-564; 72603-326; 16714-857; 43598-661; 55150-270; 0054-0382; 10019-956; 10019-957; 51407-749; 51407-750; 68001-565; 0054-0383; 72572-083; 15308-0921; 10019-936; 57821-004; 16714-859; 68001-442; 68001-444; 72603-104; 10019-982; 82920-708; 16714-858; 46708-618; 68001-443; 10019-938; 10019-943; 57884-0022; 68554-0062; 43598-660; 46708-619 |
| UNII |
8N3DW7272P
|
| Synonyms |
Cyclophosphamide | Sendoxan | B-518 | B 518 | B518 | Cyclophosphamide Anhydrous | Cyclophosphamide, (R)-Isomer | Cyclophosphamide, (S)-Isomer | Cytophosphane | Cyclophosphamide Monohydrate | Cytophosphan | Cytoxan | Endoxan | Neosar | NSC-26271 | NSC 26271 | NSC26271 | Procytox | (+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate | Cyclophosphane |
