| Pharmaceutical Information |
| Drug Name |
Cyproheptadine |
| Drug ID |
BADD_D00552 |
| Description |
Cyproheptadine is a potent competitive antagonist of both serotonin and histamine receptors.[L32474] It is used primarily to treat allergic symptoms, though it is perhaps more notable for its use in appetite stimulation[L32519] and its off-label use in the treatment of serotonin syndrome.[A231274] |
| Indications and Usage |
In the US, prescription cyproheptadine is indicated for the treatment of various allergic symptomatologies - including dermatographia, rhinitis, conjunctivitis, and urticaria - as well as adjunctive therapy in the management of anaphylaxis following treatment with epinephrine.[L32474] In Canada, cyproheptadine is available over-the-counter and is indicated for the treatment of pruritus and for appetite stimulation.[L32519] In Australia, cyproheptadine is additionally indicated for the treatment vascular headaches.[L32479]
Cyproheptadine is also used off-label for the treatment of serotonin syndrome.[A231274] |
| Marketing Status |
approved |
| ATC Code |
R06AX02 |
| DrugBank ID |
DB00434
|
| KEGG ID |
D07765
|
| MeSH ID |
D003533
|
| PubChem ID |
2913
|
| TTD Drug ID |
D00TLN
|
| NDC Product Code |
Not Available |
| UNII |
2YHB6175DO
|
| Synonyms |
Cyproheptadine | Dihexazin | Peritol | Viternum | Antergan | Periactin |
|
| Chemical Information |
| Molecular Formula |
C21H21N |
| CAS Registry Number |
129-03-3 |
| SMILES |
CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1 |
| Chemical Structure |
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| ADRs Induced by Drug |
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