Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dalfampridine
Drug ID BADD_D00574
Description Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. FDA approved on January 22, 2010.
Indications and Usage Dalfampridine is a neurofunctional modifier that helps improve walking speed in patients with multiple sclerosis (MS).
Marketing Status approved
ATC Code N07XX07
DrugBank ID DB06637
KEGG ID D04127
MeSH ID D015761
PubChem ID 1727
TTD Drug ID D08YIN
NDC Product Code 10144-427; 63190-0510; 67877-444; 56125-427; 0591-2533; 65862-917; 62756-429; 63629-9450; 65862-863; 38779-3205; 42571-338; 51927-5030; 42571-275; 0378-4504; 12817-054; 46016-5042; 54382-125; 62756-038; 62991-3143; 65372-1157; 16729-292; 63190-0530; 51407-246; 0054-0479
UNII BH3B64OKL9
Synonyms 4-Aminopyridine | 4 Aminopyridine | Dalfampridine | Pymadine | VMI-103 | VMI 103 | VMI103 | 4-Aminopyridine Sustained Release | 4 Aminopyridine Sustained Release | Sustained Release, 4-Aminopyridine | Fampridine-SR | Fampridine SR
Chemical Information
Molecular Formula C5H6N2
CAS Registry Number 504-24-5
SMILES C1=CN=CC=C1N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Rash papular23.03.13.0170.001184%Not Available
Seizure17.12.03.0010.041668%
Sensory loss17.02.07.0070.001830%Not Available
Skin disorder23.03.03.0070.002369%Not Available
Skin papilloma23.10.01.002; 11.05.07.001; 16.26.01.0020.001830%
Skin ulcer24.04.03.007; 23.07.03.0030.003015%
Sleep disorder19.02.04.0010.007591%Not Available
Sluggishness08.01.01.0040.002100%Not Available
Small intestinal obstruction07.13.06.0010.001454%
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.0030.007375%Not Available
Staring19.01.01.0030.001454%Not Available
Stress19.06.02.0040.010229%Not Available
Swelling08.01.03.0150.011790%Not Available
Tearfulness19.15.02.0050.001184%Not Available
Tension19.06.02.0050.001830%Not Available
Therapeutic response unexpected08.06.01.0010.034077%Not Available
Thinking abnormal17.02.05.023; 19.10.03.0010.002100%Not Available
Throat irritation22.12.03.029; 07.05.05.0370.008237%Not Available
Thyroid disorder05.02.01.0020.001184%Not Available
Tonic convulsion17.12.03.0110.000538%Not Available
Toothache07.09.06.0010.001830%
Transient ischaemic attack24.04.06.005; 17.08.04.0010.002530%
Tremor17.01.06.0020.031870%
Trigeminal neuralgia17.04.08.0010.008129%Not Available
Urge incontinence20.02.02.0080.001830%Not Available
Urinary hesitation20.02.02.0090.004845%Not Available
Urinary incontinence20.02.02.010; 17.05.01.0080.008937%
Urinary retention20.02.02.0110.005276%
Urinary tract disorder20.08.01.0010.005760%Not Available
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