Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Danazol
Drug ID BADD_D00576
Description A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Indications and Usage For the treatment of endometriosis and fibrocystic breast disease (in patients unresponsive to simple measures). Also used for the prophylactic treatment of all types of hereditary angioedema in males and females.
Marketing Status approved
ATC Code G03XA01
DrugBank ID DB01406
KEGG ID D00289
MeSH ID D003613
PubChem ID 28417
TTD Drug ID D09IPV
NDC Product Code 38779-0174; 0555-0635; 0555-0633; 62135-477; 0527-1369; 71205-862; 0527-1392; 53104-7501; 71052-662; 62135-476; 62135-475; 0527-1368; 49452-2436; 71205-861; 49076-5201; 0555-0634
UNII N29QWW3BUO
Synonyms Danazol | Danazant | Panacrine | Danocrine | Ladogal | Cyclomen | Danatrol | Danol | Danoval | Norciden | Azol | Danazol-Ratiopharm | Danazol Ratiopharm
Chemical Information
Molecular Formula C22H27NO2
CAS Registry Number 17230-88-5
SMILES CC12CCC3C(C1CCC2(C#C)O)CCC4=CC5=C(CC34C)C=NO5
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nervousness19.06.02.003--Not Available
Oedema14.05.06.010; 08.01.07.0060.003541%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.0070.002361%
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Peliosis hepatis09.01.07.010--Not Available
Pelvic pain21.10.01.001; 20.02.03.007; 07.01.06.012--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Photosensitivity reaction23.03.09.003--
Pleuritic pain22.12.01.007--
Polycythaemia01.07.01.001--Not Available
Premature baby18.04.02.0010.002361%Not Available
Presyncope02.11.04.013; 24.06.02.010; 17.02.05.0090.002361%
Protein total abnormal13.09.01.008--Not Available
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.0030.002361%
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rash papular23.03.13.017--Not Available
Rash vesicular23.03.13.009--Not Available
Red blood cell count increased13.01.05.008--Not Available
Seborrhoea23.02.07.001--Not Available
Seborrhoeic dermatitis23.03.04.018--Not Available
Seizure17.12.03.001--
Semen volume abnormal13.20.04.004--Not Available
Shock24.06.02.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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