Pharmaceutical Information |
Drug Name |
Daunorubicin citrate |
Drug ID |
BADD_D00591 |
Description |
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms. |
Indications and Usage |
For remission induction in acute nonlymphocytic leukemia (myelogenous, monocytic, erythroid) of adults and for remission induction in acute lymphocytic leukemia of children and adults.
Daunorubicin is indicated in combination with [cytarabine] for the treatment of newly-diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC) in adults and pediatric patients 1 year and older.[L32843] |
Marketing Status |
approved |
ATC Code |
L01DB02 |
DrugBank ID |
DB00694
|
KEGG ID |
D10787
|
MeSH ID |
D003630
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PubChem ID |
9961878
|
TTD Drug ID |
D01XWG
|
NDC Product Code |
Not Available |
UNII |
5L84T2Z6NP
|
Synonyms |
Daunorubicin | Daunomycin | Rubomycin | Dauno-Rubidomycine | Dauno Rubidomycine | Rubidomycin | Daunoblastin | Daunoblastine | NSC-82151 | NSC 82151 | NSC82151 | Cerubidine | Daunorubicin Hydrochloride | Hydrochloride, Daunorubicin |
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Chemical Information |
Molecular Formula |
C33H37NO17 |
CAS Registry Number |
371770-68-2 |
SMILES |
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O.
C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
Chemical Structure |
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ADRs Induced by Drug |
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