| Pharmaceutical Information |
| Drug Name |
Deoxycholic acid |
| Drug ID |
BADD_D00609 |
| Description |
Deoxycholic acid is a a bile acid which emulsifies and solubilizes dietary fats in the intestine, and when injected subcutaneously, it disrupts cell membranes in adipocytes and destroys fat cells in that tissue. In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity. It is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical procedures. |
| Indications and Usage |
For improvement in appearance of moderate to severe fullness associated with submental fat in adults. |
| Marketing Status |
approved |
| ATC Code |
D11AX24 |
| DrugBank ID |
DB03619
|
| KEGG ID |
D10781
|
| MeSH ID |
D003840
|
| PubChem ID |
222528
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
61168-101; 66039-937; 50384-0151 |
| UNII |
005990WHZZ
|
| Synonyms |
Deoxycholic Acid | Desoxycholic Acid | Dihydroxycholanoic Acid | Choleic Acid | Deoxycholate | Deoxycholic Acid, 12beta-Isomer | 12beta-Isomer Deoxycholic Acid | Deoxycholic Acid, 12beta Isomer | Deoxycholic Acid, 3beta-Isomer | 3beta-Isomer Deoxycholic Acid | Deoxycholic Acid, 3beta Isomer | Deoxycholic Acid, 5alpha-Isomer | 5alpha-Isomer Deoxycholic Acid | Deoxycholic Acid, 5alpha Isomer | Deoxycholic Acid, Magnesium (2:1) Salt | Deoxycholic Acid, Monoammonium Salt | Deoxycholic Acid, Monopotassium Salt | Deoxycholic Acid, Monosodium Salt | Sodium Deoxycholate | Deoxycholate, Sodium | Deoxycholic Acid, Sodium Salt, 12beta-Isomer | Lagodeoxycholic Acid | Kybella | Deoxycholic Acid, Disodium Salt |
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| Chemical Information |
| Molecular Formula |
C24H40O4 |
| CAS Registry Number |
83-44-3 |
| SMILES |
CC(CCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C |
| Chemical Structure |
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| ADRs Induced by Drug |
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