| Pharmaceutical Information |
| Drug Name |
Desloratadine |
| Drug ID |
BADD_D00615 |
| Description |
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. |
| Indications and Usage |
For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria. |
| Marketing Status |
approved; investigational |
| ATC Code |
R06AX27 |
| DrugBank ID |
DB00967
|
| KEGG ID |
D03693
|
| MeSH ID |
C121345
|
| PubChem ID |
124087
|
| TTD Drug ID |
D01GBY
|
| NDC Product Code |
53104-7613; 55111-360; 52408-0130; 66577-018; 68180-153; 62993-0805; 75895-0099; 78206-188; 65015-698; 69543-107; 71335-1000; 65691-0057; 66039-830; 50090-3975; 78206-119; 53104-7688; 62331-019; 50090-4794; 62250-619; 42291-240; 55111-551; 55111-073 |
| UNII |
FVF865388R
|
| Synonyms |
desloratadine | descarboethoxyloratadine | SCH 34117 | SCH-34117 | Clarinex | Neoclarityn | Aerius | descarboethoxyloratadine acetate |
|
| Chemical Information |
| Molecular Formula |
C19H19ClN2 |
| CAS Registry Number |
100643-71-8 |
| SMILES |
C1CC2=C(C=CC(=C2)Cl)C(=C3CCNCC3)C4=C1C=CC=N4 |
| Chemical Structure |
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| ADRs Induced by Drug |
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