Drug Name |
Desogestrel |
Drug ID |
BADD_D00618 |
Description |
Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada.[A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological activity.[T521] Desogestrel is now produced semi-synthetically from naturally occurred plant steroids.[F4127] In the US, desogestrel is found only in combination with [ethinyl estradiol].[A176342] The first approved drug containing desogestrel was developed by Organon USA Inc in 1972 and FDA approved in 1992.[L5762] |
Indications and Usage |
Oral desogestrel is used in combination with [ethinylestradiol] as a contraceptive agent for the prevention of pregnancy.[FDA label]
Desogestrel is part of the combined oral contraceptives that contain a mix of estrogen and progestin which inhibit ovulation.[L5698] |
Marketing Status |
approved |
ATC Code |
G03AC09 |
DrugBank ID |
DB00304
|
KEGG ID |
D02367
|
MeSH ID |
D017135
|
PubChem ID |
40973
|
TTD Drug ID |
D06CGB
|
NDC Product Code |
45541-1191; 55486-1569; 63190-0770; 60870-0460; 63190-0070 |
UNII |
81K9V7M3A3
|
Synonyms |
Desogestrel | 13-Ethyl-11-methylene-18,19-dinor-17 alpha-pregn-4-en-20-yn-17-ol | 13 Ethyl 11 methylene 18,19 dinor 17 alpha pregn 4 en 20 yn 17 ol | alpha-pregn-4-en-20-yn-17-ol, 13-Ethyl-11-methylene-18,19-dinor-17 | 18,19-Dinorpregn-4-en-20-yn-17-ol, 13-ethyl-11-methylene-, (17alpha)- | Org-2969 | Org 2969 | Org2969 | Marvelon | Cerazette |