Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dextromethorphan hydrobromide
Drug ID BADD_D00639
Description Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957.[A215412,L14997]
Indications and Usage Dextromethorphan is indicated in combination with [brompheniramine] and [pseudoephedrine] in the treatment of coughs and upper respiratory symptoms associated with allergies or the common cold.[L14366] Dextromethorphan is also used in combination with [guaifenesin] as an over-the-counter product to relieve a cough.[L14369] Dextromethorphan in combination with [quinidine] is indicated in the treatment of pseudobulbar affect.[L14363]
Marketing Status approved
ATC Code R05DA09
DrugBank ID DB00514
KEGG ID D00848
MeSH ID D003915
PubChem ID 5464025
TTD Drug ID D0J8RR
NDC Product Code 72854-351; 62991-1042; 81999-0009; 83167-001; 51316-778; 59779-433; 63868-222; 70893-0012; 58793-004; 65862-924; 37000-447; 0031-8743; 0363-0300; 68210-6010; 60155-002; 66174-0085; 75856-103; 41163-300; 0031-8694; 68210-4133; 68210-4181; 70893-0011; 68210-4074; 24385-493; 36800-300; 0031-9302; 68210-0005; 71309-601; 57218-760; 51013-125; 70692-778; 49452-2500; 62350-0081; 70761-101; 41250-473; 41520-903; 49873-301; 51013-161; 68210-0106; 76281-503; 11014-0206; 38779-0355; 51552-0121; 62331-003; 36800-415; 51927-0260; 68166-004; 70966-0031; 73056-019; 63868-824; 68210-0121; 55629-011; 61281-6500; 66577-042; 41250-066; 58809-850
UNII 9D2RTI9KYH
Synonyms Dextromethorphan | d-Methorphan | Dextromethorphan, (+-)-Isomer | l-Methorphan | Levomethorphan | Dextromethorphan Hydrobromide, Monohydrate | Delsym | Dextromethorphan Hydrobromide | Hydrobromide, Dextromethorphan | Dextromethorphan Hydrobromide, (+-)-Isomer | Dextromethorphan Hydrochloride | Hydrochloride, Dextromethorphan | Racemethorphan
Chemical Information
Molecular Formula C18H26BrNO
CAS Registry Number 125-69-9
SMILES CN1CCC23CCCCC2C1CC4=C3C=C(C=C4)OC.Br
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Headache17.14.01.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
The 1th Page    1    Total 1 Pages