Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dextrose monohydrate
Drug ID BADD_D00641
Description Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation.[A19399] It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative.[T28] The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated.[L786] Glucose is listed on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
Indications and Usage Glucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used for metabolic disorders such as hypoglycemia.[L787]
Marketing Status approved; investigational; vet_approved
ATC Code V06DC01; V04CA02; B05CX01
DrugBank ID DB01914
KEGG ID D02325
MeSH ID D005947
PubChem ID 22814120
TTD Drug ID D0C1FY
NDC Product Code 0990-7930; 0338-0023; 0338-0204; 0338-0551; 65219-240; 71872-7057; 0990-7922; 17271-721; 63323-624; 0409-7100; 76329-3301; 76329-3302; 0409-7517; 71872-7102; 71872-7282; 0338-0017; 0338-0062; 65219-236; 65219-238; 71872-7003; 69507-001; 0338-0066; 0338-0082; 0338-0211; 65219-234; 0409-1775; 50516-001; 0990-7923; 0990-7938; 51662-1493; 0338-0074; 0338-0216; 0338-9147; 0404-9845; 71872-7214; 51662-1453; 63323-824; 0404-9847; 0409-4902; 40087-1001; 17271-720; 0338-0070; 0338-0174; 0338-0176; 0338-0208; 0990-7120; 52584-517; 0338-0078; 0338-0170; 0338-0719; 0338-9143; 71872-7176; 0409-6648; 52647-001; 51662-1584; 52584-648; 0338-0172
UNII LX22YL083G
Synonyms Glucose | D-Glucose | D Glucose | Dextrose | Glucose, (alpha-D)-Isomer | Anhydrous Dextrose | Dextrose, Anhydrous | Glucose, (DL)-Isomer | Glucose, (L)-Isomer | L-Glucose | L Glucose | Glucose Monohydrate | Monohydrate, Glucose | Glucose, (beta-D)-Isomer
Chemical Information
Molecular Formula C6H14O7
CAS Registry Number 77938-63-7
SMILES C(C(C(C(C(C=O)O)O)O)O)O.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Confusional state17.02.03.005; 19.13.01.001--
Dehydration14.05.05.001--
Extravasation08.01.03.008--Not Available
Hyperosmolar state14.05.01.005--Not Available
Hypervolaemia02.05.04.019; 14.05.06.003--Not Available
Injection site infection11.01.08.005; 08.02.03.019; 12.07.03.008--Not Available
Loss of consciousness17.02.04.004--Not Available
Phlebitis24.12.03.004; 12.02.01.002--
Pyrexia08.05.02.003--
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