Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status approved
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 51552-1582; 58159-039; 51927-0297; 14501-0096; 0254-1010; 45562-1740; 69575-4025; 0575-6200; 38779-0324; 52952-003; 38779-3184; 51927-2742; 62991-2857; 71052-664; 13517-100
UNII O5CB12L4FN
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Ageusia17.02.07.001; 07.14.03.003--Not Available
Albuminuria20.02.01.001--Not Available
Anaemia01.03.02.0010.000329%
Angina pectoris24.04.04.002; 02.02.02.002--
Anxiety19.06.02.002--
Arrhythmia supraventricular02.03.03.001--Not Available
Aspartate aminotransferase increased13.03.04.011--
Asthenia08.01.01.001--Not Available
Azotaemia20.01.01.001--Not Available
Back pain15.03.04.005--
Blood creatinine decreased13.13.01.003--Not Available
Blood immunoglobulin G decreased13.06.05.001--Not Available
Blood urea increased13.13.01.006--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Breast mass21.05.04.002--Not Available
Cardiac failure02.05.01.0010.000219%
Cardiac failure congestive02.05.01.0020.000439%Not Available
Cataract06.06.01.001--
Cellulitis23.11.02.004; 11.02.01.001--Not Available
Cerebral ischaemia24.04.06.003; 17.08.01.005--
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Chest pain08.01.08.002; 02.02.02.011; 22.12.02.003--Not Available
Choking sensation22.12.03.004; 19.01.02.002--Not Available
Condition aggravated08.01.03.0040.000329%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctival haemorrhage24.07.05.001; 06.07.01.001--Not Available
Constipation07.02.02.001--
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