Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Diazoxide
Drug ID BADD_D00649
Description A benzothiadiazine derivative that is a peripheral vasodilator used for hypertensive emergencies. It lacks diuretic effect, apparently because it lacks a sulfonamide group.
Indications and Usage Used parentally to treat hypertensive emergencies. Also used to treat hypoglycemia secondary to insulinoma.
Marketing Status approved
ATC Code C02DA01; V03AH01
DrugBank ID DB01119
KEGG ID D00294
MeSH ID D003981
PubChem ID 3019
TTD Drug ID D07WEP
NDC Product Code 51552-1582; 58159-039; 51927-0297; 14501-0096; 0254-1010; 45562-1740; 69575-4025; 0575-6200; 38779-0324; 52952-003; 38779-3184; 51927-2742; 62991-2857; 71052-664; 13517-100
UNII O5CB12L4FN
Synonyms Diazoxide | Proglycem | Hyperstat
Chemical Information
Molecular Formula C8H7ClN2O2S
CAS Registry Number 364-98-7
SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Palpitations02.11.04.012--
Pancreatitis07.18.01.001--
Pancreatitis acute07.18.01.002--Not Available
Pancreatitis necrotising07.18.01.004--Not Available
Papilloedema24.03.07.001; 17.07.02.004; 06.09.02.002--
Paraesthesia17.02.06.005; 23.03.03.094--
Paralysis17.01.04.004--Not Available
Parotid gland enlargement07.06.03.001--Not Available
Polyneuropathy17.09.03.012--Not Available
Pruritus23.03.12.001--
Pulmonary hypertension24.08.03.002; 22.06.01.0010.001097%
Pulmonary oedema02.05.02.003; 22.01.03.0030.000219%
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Respiratory failure22.02.06.002; 14.01.04.0030.000219%
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.0010.000329%
Sleep disorder19.02.04.0010.000219%Not Available
Somnolence19.02.05.003; 17.02.04.006--
Supraventricular tachycardia02.03.03.0120.000219%
Tachycardia02.03.02.007--Not Available
Thrombocytopenia01.08.01.0020.000219%Not Available
Tricuspid valve incompetence02.07.05.0010.000219%Not Available
Vascular pain24.03.02.026--Not Available
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Ventricular arrhythmia02.03.04.006--
Vision blurred06.02.06.007; 17.17.01.010--
Visual field defect17.17.01.001; 06.02.07.003--Not Available
Vomiting07.01.07.003--
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