Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dinoprost tromethamine
Drug ID BADD_D00683
Description The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Indications and Usage Used for aborting second-trimester pregnancy (between the twelfth to eighteenth week of gestation) and in incomplete abortion or for therapeutic abortion in cases of intrauterine fetal death and congenital abnormalities incompatible with life. Also used at low-doses for medically indicated induction of labor at term. Also injected intra-arterially for use as a vasodilator to assist in angiography.
Marketing Status approved; vet_approved
ATC Code Not Available
DrugBank ID DB01160
KEGG ID D01352
MeSH ID C010714
PubChem ID 5282415
TTD Drug ID D04RGA
NDC Product Code 69870-088; 0009-5031
UNII CT6BBQ5A68
Synonyms dinoprost tromethamine | PGF2alpha tromethamine | prostaglandin F2alpha tromethamine | Lutalyse | Minprostin F2 Alpha | Prostin F2 | Prostin F2 Alpha
Chemical Information
Molecular Formula C24H45NO8
CAS Registry Number 38562-01-5
SMILES CCCCCC(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O.C(C(CO)(CO)N)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Uterine pain21.07.01.008--
Uterine rupture21.07.01.009; 18.02.02.001; 12.01.15.001--Not Available
Ventricular arrhythmia02.03.04.006--
Vomiting07.01.07.003--
Ill-defined disorder08.01.03.049--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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