Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dipyridamole
Drug ID BADD_D00692
Description A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indications and Usage For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Marketing Status approved
ATC Code B01AC07
DrugBank ID DB00975
KEGG ID D00302
MeSH ID D004176
PubChem ID 3108
TTD Drug ID D0F9GE
NDC Product Code 0641-2569; 65015-782; 65404-005; 66039-917; 68382-187; 0527-1463; 71205-895; 0115-1070; 0115-1071; 0115-1072; 51407-627; 62559-237; 69584-183; 0527-1461; 51407-626; 65841-662; 62559-236; 64980-133; 65841-663; 65841-664; 69584-182; 51407-628; 51662-1447; 0404-9852; 62559-235; 68382-188; 69584-181; 17511-122; 64980-134; 51927-1571; 68166-003; 71205-894; 71205-896; 64980-135; 68382-189; 0527-1462; 12660-0084
UNII 64ALC7F90C
Synonyms Dipyridamole | Dipyramidole | Apo-Dipyridamole | Apo Dipyridamole | Cerebrovase | Persantine | Persantin | Curantil | Curantyl | Kurantil | Miosen | Novo-Dipiradol | Novo Dipiradol | Antistenocardin | Cléridium
Chemical Information
Molecular Formula C24H40N8O4
CAS Registry Number 58-32-2
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abdominal pain upper07.01.05.0030.007126%
Alopecia23.02.02.001--
Anaemia01.03.02.001--
Anaphylactic shock10.01.07.002; 24.06.02.004--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.0020.000976%
Atrioventricular block02.03.01.002--Not Available
Atrioventricular block complete02.03.01.0030.001464%
Atrioventricular block second degree02.03.01.0050.002928%
Back pain15.03.04.005--
Bone disorder15.02.04.004--Not Available
Bradycardia02.03.02.002--Not Available
Breast pain21.05.05.003--
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.001--
Cardiomyopathy02.04.01.001--Not Available
Cerebral haemorrhage24.07.04.001; 17.08.01.0030.003904%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.001464%
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Cholelithiasis09.03.01.002--Not Available
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