Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Dipyridamole
Drug ID BADD_D00692
Description A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Indications and Usage For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
Marketing Status approved
ATC Code B01AC07
DrugBank ID DB00975
KEGG ID D00302
MeSH ID D004176
PubChem ID 3108
TTD Drug ID D0F9GE
NDC Product Code 0641-2569; 65015-782; 65404-005; 66039-917; 68382-187; 0527-1463; 71205-895; 0115-1070; 0115-1071; 0115-1072; 51407-627; 62559-237; 69584-183; 0527-1461; 51407-626; 65841-662; 62559-236; 64980-133; 65841-663; 65841-664; 69584-182; 51407-628; 51662-1447; 0404-9852; 62559-235; 68382-188; 69584-181; 17511-122; 64980-134; 51927-1571; 68166-003; 71205-894; 71205-896; 64980-135; 68382-189; 0527-1462; 12660-0084
UNII 64ALC7F90C
Synonyms Dipyridamole | Dipyramidole | Apo-Dipyridamole | Apo Dipyridamole | Cerebrovase | Persantine | Persantin | Curantil | Curantyl | Kurantil | Miosen | Novo-Dipiradol | Novo Dipiradol | Antistenocardin | Cléridium
Chemical Information
Molecular Formula C24H40N8O4
CAS Registry Number 58-32-2
SMILES C1CCN(CC1)C2=NC(=NC3=C2N=C(N=C3N4CCCCC4)N(CCO)CCO)N(CCO)CCO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Circulatory collapse24.06.02.0010.000976%Not Available
Coordination abnormal17.02.02.004--Not Available
Coronary artery disease02.02.01.001; 24.04.04.006--Not Available
Cough22.02.03.001--
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dysphonia22.12.03.006; 19.19.03.002; 17.02.08.004--
Dyspnoea02.11.05.003; 22.02.01.004--
Ear pain04.03.01.003--
Electrocardiogram abnormal13.14.05.001--Not Available
Eructation07.01.02.003--
Extrasystoles02.03.02.003--Not Available
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage07.12.02.001; 24.07.02.0090.000976%Not Available
Gastrointestinal pain07.01.05.005--
Generalised tonic-clonic seizure17.12.01.002--Not Available
Haematuria24.07.01.047; 20.02.01.006; 21.10.01.018--
Haemoglobin13.01.05.018--Not Available
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